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Research Grade Timdarpacept
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  • Catalog： TD-HX892106
  • Clonality： mAb
  • Application： Research Grade Biosimilar
  • Synonyms： CAS:2749520-17-8
  • 规格：
    1mg
  • 价格：
    ¥询价
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Research Grade Timdarpacept

Catalog No. TD-HX892106
Species reactivity Human
Applications Research Grade Biosimilar
Isotype Fusion-[human signal-regulatory protein alpha (SIRPα) receptor domain 1 fragment (1-133) natural variant V2 (SIRPα V2)]2-IgG1-Fc (Fragment constant)
Expression system Mammalian Cells
Clonality Monoclonal
Target BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Purified by nickel column chromatography.
Accession P78324
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names CAS:2749520-17-8
Background Timdarpacept (DNL310) is a recombinant SIRPa-Fc fusion protein that can activate macrophages to enhance anti-tumor activity by blocking CD47-SIRPa.
Note For research use only. Not for use in clinical or therapeutic applications.