| Catalog No. |
TD-HX959046 |
| Species reactivity |
Human |
| Applications |
Research Grade Biosimilar |
| Host species |
Humanized |
| Isotype |
(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc |
| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Tumor necrosis factor receptor superfamily member 17, TNFRSF17, CD269, B-cell maturation protein, BCMA, BCM, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G, purified from cell culture supernatant. |
| Accession |
Q02223 & P07766 |
| Form |
Liquid |
| Storage buffer |
30mM Histidine,pH5.8,10% Sucrose,0.06% Tween80. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names |
Bispecific,AMG-420,AMG420,BI-836909,CAS:2251756-52-0 |
| Background |
Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines. |
| Note |
For research use only. Not for use in clinical or therapeutic applications. |
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