H27K15 is a monoclonal antibody targeting human CSF-1R. It partially inhibits CSF-1R signaling, prevents monocyte differentiation into M2-polarized macrophages, and promotes dendritic cell development. H27K15 has been tested in preclinical cancer models, showing potential to modulate the tumor microenvironment and reduce treatment-related rebound effects.
Protein A/G purified from cell culture supernatant.
Accession
P07333
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Caption
SDS-PAGE for InVivoMAb Anti-Human CD115/CSF1R Antibody (H27K15) | Detects CD115 in indirect ELISA. | Western blot analysis was performed using anti-CD115/CSF1R monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human CD115/CSF1R (Catalog No.:TD-HY035011)Lane 2:negative control
Note
For research use only. Not suitable for clinical or therapeutic use.