EN
抗体药类似物
Research Grade Atibuclimab
All
  • CatalogTD-HY038016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • Synonyms28C5, termed IC14, CAS: 2417175-94-9
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Atibuclimab


Catalog No. TD-HY038016
Species reactivity Human
Applications Research Grade Biosimilar
Host species Chimeric
Isotype IgG4-kappa
Expression system Mammalian Cells
Species Human
Clonality Monoclonal
Target Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P08571
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names 28C5, termed IC14, CAS: 2417175-94-9
Background Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist.
Note For research use only. Not suitable for clinical or therapeutic use.