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Research Grade Tebentafusp
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TD-HY057066_1.jpg
- Catalog： TD-HY057066
- Clonality： mAb
- Application： Research Grade Biosimilar
- Synonyms： Bispecific fusion protein, CAS: 1874157-95-5
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规格：
1mg
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价格：
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Research Grade Tebentafusp
| Catalog No. | TD-HY057066 |
|---|---|
| Species reactivity | Human |
| Applications | Research Grade Biosimilar |
| Host species | Humanized |
| Isotype | scFv-TCR |
| Expression system | Mammalian Cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | CD3E, gp100 peptide-HLA Complex, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, T-cell surface glycoprotein CD3 epsilon chain |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Purified by Nickel column. |
| Accession | P07766 |
| Form | Liquid |
| Storage buffer | 9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, 2mM DTT, pH 6.5. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternate Names | Bispecific fusion protein, CAS: 1874157-95-5 |
| Background | Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A*02:01 (a melanoma-associated antigen). Tebentafusp guides T cells to kill gp100-expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain. Tebentafusp leads to inflammatory cytokines and cytolytic proteins production, resulting in the direct lysis of tumour cells. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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SDS-PAGE for Research Grade Tebentafusp. |