Catalog No. |
TD-HY105016 |
Species reactivity |
Human |
Applications |
Research Grade Biosimilar |
Host species |
Humanized |
Isotype |
IgG1-kappa |
Expression system |
Mammalian Cells |
Clonality |
Monoclonal |
Target |
FLT2, HBGFR, BFGFR, FGFR-1, CEK, Fibroblast growth factor receptor 1, FGFR1, bFGF-R-1, Fms-like tyrosine kinase 2, FGFBR, FLT-2, CD331, Basic fibroblast growth factor receptor 1, FLG, Proto-oncogene c-Fgr, N-sam, Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL |
Endotoxin level |
Please contact the lab for this information. |
Purity |
>95% purity as determined by SDS-PAGE. |
Purification |
Protein A/G, purified from cell culture supernatant. |
Accession |
P11362 & Q86Z14 |
Form |
Liquid |
Storage buffer |
0.01M PBS,pH7.4. |
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names |
Bispecific,BFKB8488A,CAS:2517935-02-1 |
Background |
Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD). |
Note |
For research use only. Not for use in clinical or therapeutic applications. |