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抗体药类似物
Research Grade Onartuzumab
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  • CatalogTD-HY196026
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • SynonymstMAb,OA-5DMe5,PRO143966,CAS:1133766-06-9
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Onartuzumab


Catalog No. TD-HY196026
Species reactivity Human
Applications Research Grade Biosimilar
Host species Humanized
Isotype Fab-G1-kappa-[Fc-G1]
Expression system Mammalian Cells
Clonality Monoclonal
Target Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession P08581
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names tMAb,OA-5DMe5,PRO143966,CAS:1133766-06-9
Background Onartuzumab (MetMAb) is a unique, humanized and affinity-matured monovalent (one-armed) monoclonal antibody against the MET receptor. Onartuzumab potently inhibits HGF binding and receptor phosphorylation and signaling. Onartuzumab has antibody-like pharmacokinetics and antitumor activity.
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 
SEC-HPLC detection for Research Grade Onartuzumab.
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SDS-PAGE
 
SDS-PAGE for Research Grade Onartuzumab.