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抗体药类似物
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Research Grade Sotatercept
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SDS-PAGE
  • Catalog： TD-HY428026
  • Clonality：
  • Application： ELISA, Functional assay, Research in vivo
  • Synonyms： ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-HY428026
  • Description
    Sotatercept(TD-HY428026) is a research-grade recombinant antibody targetingEDF. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Human
  • Applications
    ELISA, Functional assay, Research in vivo
  • Isotype
    Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant)
  • Target
    EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P08476
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7
  • Background
    Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions.
  • Caption
    SDS-PAGE for Research Grade Sotatercept
  • Note
    For research use only. Not suitable for clinical or therapeutic use.