TD-HY564046

Ivicentamab(TD-HY564046) is a research-grade recombinant antibody targetingCD37. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Human

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Humanized

IgG1-kappa

Monoclonal

CD37, Tspan-26, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

P11049

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

DuoHexaBody-CD37, GEN3009, GEN-3009, GEN30092364496-42-2

Ivicentamab (GEN-3009) is an IgG1κ anti-CD37 humanized monoclonal antibody. Ivicentamab can be used for cancer research.

SEC-HPLC detection for Research Grade Ivicentamab. ### Detects recombinant human CD37 (Catalog No:TD-HY564012) in indirect ELISA　　|　SDS-PAGE for Research Grade Ivicentamab.　　|　Flow-cytometry using APC anti-human CD37 antibody. Raji cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD37 monoclonal antibody (Catalog: HY564046, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer. ### Flow-cytometry using FITC anti-human CD37 antibody. Raji cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD37 monoclonal antibody (Catalog: HY564046, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer. ### Flow-cytometry using PE anti-human CD37 antibody. Raji cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD37 monoclonal antibody (Catalog: HY564046, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.　　|　Western blot analysis was performed using anti-CD37 monoclonal antibody at 1ug/mL on various samples.Lane 1:recombinant human CD37 (Catalog No:TD-HY564012)Lane 2:negative control

For research use only. Not suitable for clinical or therapeutic use.