TD-JN060016

Tefibazumab(TD-IN060016) is a research-grade recombinant antibody targetingclfAClumping factor A. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Staphylococcus aureus

ELISA, Functional assay, Research in vivo

Humanized

IgG1-kappa

Monoclonal

clfAClumping factor A

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Q53653, Q2G015, Q5HHM8

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Aurexis, 521079-87-8

Tefibazumab is a humanized IgG1κ monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A. Tefibazumab can be used for the research of serious Staphylococcus aureus infections.• Diabetic retinopathy., PMID:22455417• Novel Target for Limiting VEGF-A (Vascular Endothelial Growth Factor A)-Induced Vascular Permeability., PMID:36004641• Vascular endothelial growth factor-A as a promising therapeutic target for the management of psoriasis., PMID:32654325• Interleukin-37, vascular endothelial growth factor A, and transforming growth factor-β1: promising biomarkers in primary immune thrombocytopenia., PMID:35815383• [Research progress of vascular endothelial growth factor-A and its isoforms in kidney disease]., PMID:35199126• Life and Death of Podocytes: Not Only a Matter of Vascular Endothelial Growth Factor., PMID:26930245• Preface., PMID:30612609• Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected againstStaphylococcus aureus-induced acute circulatory failure in a mechanically ventilated rabbit model of hyperdynamic septic shock., PMID:37781371• Diabetic retinopathy., PMID:22784133• Diabetic retinopathy., PMID:22784134

SEC-HPLC detection for Research Grade Tefibazumab.　　|　SDS-PAGE for Research Grade Tefibazumab.

For research use only. Not suitable for clinical or therapeutic use.