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抗体药类似物
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Research Grade Bezlotoxumab
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Bioactivity
SDS-PAGE
  • Catalog： TD-JN876016
  • Clonality： Monoclonal
  • Application： ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Synonyms： MK-6072, CDB-1, MDX-1388, MK-3415A(combinationofactoxumabandbezlotoxumab), formerlyCDB1, 1246264-45-8
  • 规格：
    询价
  • 价格：
    ¥100ug
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  • Catalog No.
    TD-JN876016
  • Description
    Bezlotoxumab(TD-IN876016) is a research-grade recombinant antibody targetingToxin B. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.
  • Species reactivity
    Clostridioides difficile
  • Applications
    ELISA, Bioactivity: FACS, Functional assay, Research in vivo
  • Host species
    Human
  • Isotype
    IgG1-kappa
  • Clonality
    Monoclonal
  • Target
    Toxin B, 3.4.22.-, Glucosyltransferase TcdB, 2.4.1.-, tcdB, toxB
  • Endotoxin level
    Please contact the lab for this information.
  • Purity
    >95% purity as determined by SDS-PAGE.
  • Purification
    Protein A/G purified from cell culture supernatant.
  • Accession
    P18177
  • Form
    Liquid
  • Storage buffer
    0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
  • Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
  • Alternate Names
    MK-6072, CDB-1, MDX-1388, MK-3415A(combinationofactoxumabandbezlotoxumab), formerlyCDB1, 1246264-45-8
  • Background
    Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis.• Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A., PMID:21046073
  • Caption
    SEC-HPLC detection for Research Grade Bezlotoxumab.　　|　SDS-PAGE for Research Grade Bezlotoxumab.
  • Note
    For research use only. Not suitable for clinical or therapeutic use.