TD-JN969016

Berlimatoxumab(TD-IN969016) is a research-grade recombinant antibody targetinglukG. Produced in mammalian cells with native-like glycosylation.HighlightsResearch Grade— For PK/PD studies, assay development, and ADA research.Native Glycosylation— Mammalian expression ensures native-like patterns.

Staphylococcus aureus

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Human

IgG1-kappa

Monoclonal

lukG

Please contact the lab for this information.

>95% purity as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

A0A6B5MC52

Liquid

0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

ASN-100(combinationofatidortoxumabandberlimatoxumab), ASN-2, 1939109-24-6

Berlimatoxumab (ASN-2) is an antibody. Berlimatoxumab can be used for experiment research.• Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins., PMID:24586678• Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity., PMID:31852826• Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies., PMID:27467113• Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH., PMID:25371205• Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories., PMID:35858453• Human antibody responses against non-covalently cell wall-bound Staphylococcus aureus proteins., PMID:29459694• Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics., PMID:20661294• Serum neutralizing antibody after rabies postexposure prophylaxis., PMID:945973• Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening., PMID:29176494• Vitamin E regulates mitochondrial hydrogen peroxide generation., PMID:10490278

SEC-HPLC detection for Research Grade Berlimatoxumab.　　|　SDS-PAGE for Research Grade Berlimatoxumab.

For research use only. Not suitable for clinical or therapeutic use.