Z23 is a human monoclonal antibody isolated from a Zika virus (ZIKV) patient that potently neutralizes ZIKV by targeting its Envelope (E) protein. It provides protection in animal models, shows high specificity for ZIKV without cross-reactivity to Dengue virus, and serves as a valuable candidate for antiviral therapies and vaccine development. Structural studies reveal how Z23 blocks viral entry.
Species reactivity
Zika virus (ZIKV)
Applications
ELISA, Neutralization
Host species
Human
Isotype
IgG1-kappa
Clone ID
Z23
Clonality
Monoclonal
Target
Genome polyprotein, Envelope protein E
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
A0A024B7W1, A0A142I5B9
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Caption
SDS-PAGE for InVivoMAb Anti-ZIKV Envelope protein E Antibody (Z23)
Note
For research use only. Not suitable for clinical or therapeutic use.
抗体
试剂盒
多肽
蛋白
组织芯片
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