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抗体药类似物
Research Grade Dinutuximab
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  • CatalogTD-YP115016
  • ClonalitymAb
  • Application Research Grade Biosimilar
  • Synonyms14.18,MAb-14.18,MOABCh14.18,CAS:1363687-32-4,DGK07804
  • 规格
    1mg
  • 价格
    ¥询价
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Research Grade Dinutuximab


Catalog No. TD-YP115016
Species reactivity General
Applications Research Grade Biosimilar
Host species Chimeric
Isotype IgG1-kappa
Expression system Mammalian Cells
Clonality Monoclonal
Target Ganglioside GD2
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G, purified from cell culture supernatant.
Accession CAS: 65988-71-8
Form Liquid
Storage buffer 0.01M PBS,pH7.4.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names 14.18,MAb-14.18,MOABCh14.18,CAS:1363687-32-4,DGK07804
Background Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]).
Note For research use only. Not for use in clinical or therapeutic applications.

 

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Bioactivity
 

 

SEC-HPLC detection for Research Grade Dinutuximab.

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SDS-PAGE
 

 

SDS-PAGE for Research Grade Dinutuximab.