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Mouse Monoclonal Antibody to CD1C
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- Catalog： TD-31403
- Clonality： mAb
- Application： FCM, ELISA, IHC
- Synonyms： R7; CD1; CD1A; BDCA1
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD1C
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| Description | |
| This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been oBS/erved, but their full-length nature is not known. | |
| Specification | |
| Aliases | R7; CD1; CD1A; BDCA1 |
| Entrez GeneID | 911 |
| Swissprot | P29017 |
| clone | 3G1B3 |
| WB Predicted band size | 37.7kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD1C (AA: extra 18-302) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Flow cytometric analysis of Ramos cells using CD1C mouse mAb (green) and negative control (red). |
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD1C mouse mAb with DAB staining. |