Mouse Monoclonal Antibody to CD3E
|
| Description |
| The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. |
| Specification |
| Aliases |
T3E; TCRE; FLJ18683; CD3E |
| Entrez GeneID |
916 |
| Swissprot |
P07766 |
| clone |
4.00E+02 |
| WB Predicted band size |
23kDa |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of CD3E expressed in E. Coli. |
| Formulation |
Ascitic fluid containing 0.03% sodium azide. |
| Application |
| WB |
1/500 - 1/2000 |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |