Mouse Monoclonal Antibody to CD8
|
| Description |
| CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subs/et of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck. |
| Specification |
| Aliases |
MAL; p32; Leu2; CD8A |
| Entrez GeneID |
925 |
| Swissprot |
P01732 |
| clone |
RAVB3 |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD8 expressed in E. Coli. |
| Formulation |
Purified antibody in PBS containing 0.03% sodium azide. |
| Application |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |