Mouse Monoclonal Antibody to CD8
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Description |
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subs/et of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck. |
Specification |
Aliases |
MAL; p32; Leu2; CD8A |
Entrez GeneID |
925 |
Swissprot |
P01732 |
clone |
RAVB3 |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD8 expressed in E. Coli. |
Formulation |
Purified antibody in PBS containing 0.03% sodium azide. |
Application |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |