抗体
试剂盒
多肽
探针
蛋白
组织芯片
产品中心
Product Center
Mouse Monoclonal Antibody to CD11a
All
- Catalog： TD-31525
- Clonality： mAb
- Application： FCM, ELISA, IHC, WB
- Synonyms： ITGAL; LFA-1; LFA1A
-
规格：
100ul 50ul
-
价格：
¥2180
定制服务咨询
Mouse Monoclonal Antibody to CD11a |
|
| Description | |
| ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. | |
| Specification | |
| Aliases | ITGAL; LFA-1; LFA1A |
| Entrez GeneID | 3683 |
| Swissprot | P20701 |
| clone | 5G7C5 |
| WB Predicted band size | 128.8kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
|
|
|
| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Western blot analysis using CD11a mouse mAb against HL-60 (1), A549 (2), and SW620 (3) cell lysate. | Flow cytometric analysis of HL-60 cells using CD11a mouse mAb (green) and negative control (red). |
|
|
|
|
| Immunohistochemical analysis of paraffin-embedded human tonsil tissues using CD11a mouse mAb with DAB staining. | Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD11a mouse mAb with DAB staining. |