Rabbit Monoclonal Antibody to CD11C
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Description |
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. |
Specification |
Aliases |
ITGAX; SLEB6 |
Entrez GeneID |
3687 |
Swissprot |
P20702 |
clone |
6G2D1 |
WB Predicted band size |
127.8kDa |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD11C (AA: extra 102-279) expressed in E. Coli. |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Application |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |