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Mouse Monoclonal Antibody to CD16
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  • Catalog： TD-31387
  • Clonality： mAb
  • Application： FCM
  • Synonyms： FCGR3A; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
  • 规格：
    100ul 50ul
  • 价格：
    ¥2180
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Mouse Monoclonal Antibody to CD16
Description
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specification
Aliases FCGR3A; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
Entrez GeneID 2214
Swissprot P08637
clone 2G10A9
WB Predicted band size 29kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD16 (AA: extra 17-208) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-313871.jpg
TD-313872.jpg
  
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow cytometric analysis of Ramos cells using CD16 mouse mAb (green) and negative control (red).