Mouse Monoclonal Antibody to CD20
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Description |
CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1. |
Specification |
Aliases |
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1 |
Entrez GeneID |
931 |
Swissprot |
P11836 |
clone |
3E9D3C1G3 |
Host/Isotype |
Mouse IgG |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH. |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Application |
IHC |
1/200 - 1/1000 |
ICC |
1/200 - 1/1000 |
ELISA |
1/10000 |
Product Image |