Mouse Monoclonal Antibody to CD20
|
| Description |
| CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1. |
| Specification |
| Aliases |
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1 |
| Entrez GeneID |
931 |
| Swissprot |
P11836 |
| clone |
3E9D3C1G3 |
| Host/Isotype |
Mouse IgG |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH. |
| Formulation |
Ascitic fluid containing 0.03% sodium azide. |
| Application |
| IHC |
1/200 - 1/1000 |
| ICC |
1/200 - 1/1000 |
| ELISA |
1/10000 |
| Product Image |