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Mouse Monoclonal Antibody to CD27
All
ELISA
FCM
- Catalog： TD-31619
- Clonality： mAb
- Application： FCM
- Synonyms： T14; S152; Tp55; TNFRSF7; S152. LPFS2
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD27
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| Description | |
| The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. | |
| Specification | |
| Aliases | T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
| Entrez GeneID | 939 |
| Swissprot | P26842 |
| clone | 3B6D3 |
| WB Predicted band size | 29.1kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD27 (AA: extra 20-144) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Flow cytometric analysis of HL-60 cells using CD27 mouse mAb (green) and negative control (red). |