Mouse Monoclonal Antibody to CD30
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Description |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Specification |
Aliases |
CD30; Ki-1; D1S166E; TNFRSF8 |
Entrez GeneID |
943 |
Swissprot |
P28908 |
clone |
3B10 |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD30 expressed in E. Coli. |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Application |
WB |
1/500 - 1/2000 |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |