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Mouse Monoclonal Antibody to CD43
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- Catalog： TD-31944
- Clonality： mAb
- Application： WB, IHC, FCM
- Synonyms： LSN; SPN; GALGP; GPL115
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD43
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| Description | |
| This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. | |
| Specification | |
| liases | LSN; SPN; GALGP; GPL115 |
| Entrez GeneID | 6693 |
| Swissprot | P16150 |
| clone | 3E12F3 |
| WB Predicted band size | 40.3kda |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD43(AA: extra(20-169)) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| IHC | 1/200-1/1000 |
| FCM | 1/200-1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng) | Western blot analysis using CD43 mouse mAb against HEK293-6E (1), HEK293 (2),K562 (3), MOLT4 (4), Jurkat (5),and PANC-1 (6) cell lysate. | Flow cytometric analysis of Jurkat cells using CD43 mouse mAb (green) and negative control (red). |
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| Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CD43 mouse mAb with DAB staining. |