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Mouse Monoclonal Antibody to CD49B
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- Catalog： TD-31439
- Clonality： mAb
- Application： IF, FCM
- Synonyms： ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD49B
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| Description | |
| This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. | |
| Specification | |
| Aliases | ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2 |
| Entrez GeneID | 3673 |
| Swissprot | P17301 |
| clone | 5E3A8 |
| WB Predicted band size | 129.3kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| ICC | 1/100 - 1/500 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Immunofluorescence analysis of Hela cells using CD49B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503) | Flow cytometric analysis of HT1080 cells using CD49B mouse mAb (green) and negative control (red). |