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Mouse Monoclonal Antibody to CD49D
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- Catalog： TD-31529
- Clonality： mAb
- Application： WB, FCM
- Synonyms： ITGA4; IA4
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD49D
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| Description | |
| The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. | |
| Specification | |
| Aliases | ITGA4; IA4 |
| Entrez GeneID | 3676 |
| Swissprot | P13612 |
| clone | 7E4C5 |
| WB Predicted band size | 114.9kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD49D (AA: extra 833-977) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Western blot analysis using CD49D mouse mAb against HL-60 (1) cell lysate. | Flow cytometric analysis of HL-60 cells using CD49D mouse mAb (green) and negative control (red). |