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Mouse Monoclonal Antibody to CD49E
All
  • CatalogTD-31566
  • ClonalitymAb
  • Application FCM
  • SynonymsITGA5; FNRA; VLA-5; VLA5A
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD49E


 

Description
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Specification
Aliases ITGA5; FNRA; VLA-5; VLA5A
Entrez GeneID 3678
Swissprot P08648
clone 8D1G12
WB Predicted band size 114.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-315661.jpg

TD-315662.jpg

 
 
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow cytometric analysis of HL-60 cells using CD49E mouse mAb (green) and negative control (red).