Mouse Monoclonal Antibody to CD49E
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Description |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Specification |
Aliases |
ITGA5; FNRA; VLA-5; VLA5A |
Entrez GeneID |
3678 |
Swissprot |
P08648 |
clone |
8D1G12 |
WB Predicted band size |
114.5kDa |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli. |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Application |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |