Mouse Monoclonal Antibody to CD49E
|
| Description |
| The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
| Specification |
| Aliases |
ITGA5; FNRA; VLA-5; VLA5A |
| Entrez GeneID |
3678 |
| Swissprot |
P08648 |
| clone |
8D1G12 |
| WB Predicted band size |
114.5kDa |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli. |
| Formulation |
Purified antibody in PBS with 0.05% sodium azide |
| Application |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |