Mouse Monoclonal Antibody to CD51
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| Description |
| The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
| Specification |
| Aliases |
ITGAV; MSK8; VNRA; VTNR |
| Entrez GeneID |
3685 |
| Swissprot |
P06756 |
| clone |
3H1A5 |
| WB Predicted band size |
116kDa |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD51 (AA: extra 31-189) expressed in E. Coli. |
| Formulation |
Purified antibody in PBS with 0.05% sodium azide |
| Application |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |