抗体
试剂盒
多肽
探针
蛋白
组织芯片
产品中心
Product Center
Mouse Monoclonal Antibody to CD53
All
- Catalog： TD-31520
- Clonality： mAb
- Application： WB, IHC, FCM
- Synonyms： MOX44; TSPAN25
-
规格：
100ul 50ul
-
价格：
¥2180
定制服务咨询
Mouse Monoclonal Antibody to CD53
|
|
| Description | |
| The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. | |
| Specification | |
| Aliases | MOX44; TSPAN25 |
| Entrez GeneID | 963 |
| Swissprot | P19397 |
| clone | 7A8D3 |
| WB Predicted band size | 24.3kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD53 (AA: extra mix) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
|
|
|
| Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) | Western blot analysis using CD53 mouse mAb against Raji (1), Ramos (2), Jurkat (3), MOLT4 (4), K562 (5), HL-60 (6), THP-1 (7), and U937 (8) cell lysate. | Flow cytometric analysis of HL-60 cells using CD53 mouse mAb (green) and negative control (red). |
|
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD53 mouse mAb with DAB staining. |
Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CD53 mouse mAb with DAB staining. |