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Mouse Monoclonal Antibody to CD55
All
  • CatalogTD-30422
  • ClonalitymAb
  • Application WB, FCM
  • SynonymsCR; TC; DAF; CROM
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD55


 

Description
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Specification
Aliases CR; TC; DAF; CROM
Entrez GeneID 1604
Swissprot P08174
clone 3F12
WB Predicted band size 41.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD55 (AA: 238-357) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-304223.jpg
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
TD-304221.jpg
Western blot analysis using CD55 mouse mAb against Raji (1) and K562 (2) cell lysate.

TD-304222.jpg

Flow cytometric analysis of K562 cells using CD55 mouse mAb (green) and negative control (red).