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Mouse Monoclonal Antibody to CD74
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- Catalog： TD-30532
- Clonality： mAb
- Application： WB, IF, FCM
- Synonyms： II; DHLAG; HLADG; Ia-GAMMA
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD74
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| Description | |
| The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. | |
| Specification | |
| Aliases | II; DHLAG; HLADG; Ia-GAMMA |
| Entrez GeneID | 972 |
| Swissprot | P04233 |
| clone | 2D1B3 |
| WB Predicted band size | 33.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD74 (AA: 1-106) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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| Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); | Western blot analysis using CD74 mouse mAb against Raji cell lysate. | Immunofluorescence analysis of Hela cells using CD74 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. |
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| Immunofluorescence analysis of Hela cells using CD74 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. |