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CD85K
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- Catalog： TD-32039
- Clonality： mAb
- Application： FCM, ELISA, IHC, ICC
- Synonyms： ILT3; LIR5; LILRB4; ILT-3; LIR-5
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规格：
100ul 50ul
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价格：
¥2180
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| Mouse Monoclonal Antibody to CD85K | ||||||||||
| Description | ||||||||||
| This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | ||||||||||
| Specification | ||||||||||
| Aliases | ILT3; LIR5; LILRB4; ILT-3; LIR-5 | |||||||||
| Entrez GeneID | 11006 | |||||||||
| Swissprot | Q8NHJ6 | |||||||||
| clone | 8F1H11 | |||||||||
| WB Predicted band size | 49kDa | |||||||||
| Host/Isotype | Mouse IgG1 | |||||||||
| Antibody Type | Primary antibody | |||||||||
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |||||||||
| Species Reactivity | Human | |||||||||
| Immunogen | Purified recombinant fragment of human CD85K (AA: 22-259) expressed in E. Coli. | |||||||||
| Formulation | Purified antibody in PBS with 0.05% sodium azide | |||||||||
| Application | ||||||||||
| IHC | 1/200 - 1/1000 | |||||||||
| IF | 1/200 - 1/1000 | |||||||||
| FCM | 1/200 - 1/400 | |||||||||
| ELISA | 1/10000 | |||||||||
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