抗体
试剂盒
多肽
蛋白
组织芯片
产品中心
Product Center
Mouse Monoclonal Antibody to CD86
All
WB
- Catalog： TD-30107
- Clonality： mAb
- Application： WB
- Synonyms： B70; B7-2; LAB72; CD28LG2; MGC34413; CD86
-
规格：
100ul 50ul
-
价格：
¥2180
定制服务咨询
| Mouse Monoclonal Antibody to CD86 | |
| Description | |
| This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes. | |
| Specification | |
| Aliases | B70; B7-2; LAB72; CD28LG2; MGC34413; CD86 |
| Entrez GeneID | 942 |
| Swissprot | P42081 |
| clone | 1B3 |
| WB Predicted band size | 52kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD86 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Application | |
| WB | 1/500 - 1/2000 |
| ELISA | 1/10000 |
| Product Image | |
|
Western blot analysis using CD86 mouse mAb against L1210 (1) and MOLT-4 (2) cell lysate.
|