| Mouse Monoclonal Antibody to CD87 |
| Description |
| This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
| Specification |
| Aliases |
PLAUR; UPAR; URKR; U-PAR |
| Entrez GeneID |
5329 |
| Swissprot |
Q03405 |
| clone |
1D1B11 |
| WB Predicted band size |
37kDa |
| Host/Isotype |
Mouse IgG2b |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. Coli. |
| Formulation |
Purified antibody in PBS with 0.05% sodium azide |
| Application |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |