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CD抗体
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CD87
All
ELISA
FCM
  • CatalogTD-31502
  • ClonalitymAb
  • Application FCM
  • SynonymsPLAUR; UPAR; URKR; U-PAR
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD87
Description
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Specification
Aliases PLAUR; UPAR; URKR; U-PAR 
Entrez GeneID 5329
Swissprot Q03405 
clone 1D1B11
WB Predicted band size 37kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD87 (AA: 23-305) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-315021.jpg
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
TD-315022.jpg
Flow cytometric analysis of K562 cells using CD87 mouse mAb (green) and negative control (red).