Mouse Monoclonal Antibody to CD89 |
Description |
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Specification |
Aliases |
FCAR; FcalphaRI; CTB-61M7.2 |
Entrez GeneID |
2204 |
Swissprot |
P24071 |
clone |
2F9D8 |
WB Predicted band size |
32.3kDa |
Host/ Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD89 (AA: extra 22-227) expressed in E. Coli. |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Application |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |