| Mouse Monoclonal Antibody to CD105 |
| Description |
| This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. |
| Specification |
| Aliases |
ENG; END; ORW; HHT1; ORW1; CD105; FLJ41744 |
| Entrez GeneID |
2022 |
| Swissprot |
P17813 |
| clone |
3A9 |
| WB Predicted band size |
71kDa |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD105 expressed in E. Coli. |
| Formulation |
Purified antibody in PBS with 0.05% sodium azide. |
| Application |
| IHC |
1/200 - 1/1000 |
| IF |
1/200 - 1/1000 |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |