Description |
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
Specification |
Aliases |
NECTIN3; PPR3; PRR3; PVRL3; PVRR3; CDW113; NECTIN-3 |
Entrez GeneID |
25945 |
Swissprot |
Q9NQS3 |
clone |
6D5B2 |
WB Predicted band size |
61kDa |
Host/Isotype |
Mouse IgG1 |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD113 (AA: extra 282-404) expressed in E. Coli. |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Application |
FCM |
1/200 - 1/400 |
ELISA |
1/10000 |
Product Image |