| Description |
| This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
| Specification |
| Aliases |
NECTIN3; PPR3; PRR3; PVRL3; PVRR3; CDW113; NECTIN-3 |
| Entrez GeneID |
25945 |
| Swissprot |
Q9NQS3 |
| clone |
6D5B2 |
| WB Predicted band size |
61kDa |
| Host/Isotype |
Mouse IgG1 |
| Antibody Type |
Primary antibody |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity |
Human |
| Immunogen |
Purified recombinant fragment of human CD113 (AA: extra 282-404) expressed in E. Coli. |
| Formulation |
Purified antibody in PBS with 0.05% sodium azide |
| Application |
| FCM |
1/200 - 1/400 |
| ELISA |
1/10000 |
| Product Image |