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CD118
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ELISA
FCM
- Catalog： TD-31820
- Clonality： mAb
- Application： FCM, ELISA
- Synonyms： LIFR; SWS; SJS2; STWS; LIF-R
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD118
| Description | |
| This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. | |
| Specification | |
| Aliases | LIFR; SWS; SJS2; STWS; LIF-R |
| Entrez GeneID | 3977 |
| Swissprot | P42702 |
| clone | 5D3G12 |
| WB Predicted band size | 123.7kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of THP-1 cells using CD118 mouse mAb (green) and negative control (red).
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