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CD124
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ELISA
FCM
- Catalog： TD-31844
- Clonality： mAb
- Application： FCM, ELISA
- Synonyms： IL4R; IL4RA; IL-4RA
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD124
| Description | |
| This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. | |
| Specification | |
| Aliases | IL4R; IL4RA; IL-4RA |
| Entrez GeneID | 3566 |
| Swissprot | P24394 |
| clone | 4B12B12 |
| WB Predicted band size | 89.7kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD124 (AA: 26-232) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HL-60 cells using CD124 mouse mAb (green) and negative control (red).
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