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CD125
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ELISA
FCM
- Catalog： TD-31604
- Clonality： mAb
- Application： FCM
- Synonyms： IL5RA; IL5R; CDw125; HSIL5R3
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD125
| Description | |
| The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. | |
| Specification | |
| Aliases | IL5RA; IL5R; CDw125; HSIL5R3 |
| Entrez GeneID | 3568 |
| Swissprot | Q01344 |
| clone | 5E12F5D6 |
| WB Predicted band size | 47.7kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD125 (AA: extra 21-196) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HL-60 cells using CD125 mouse mAb (green) and negative control (red).
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