Description |
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. |
Specification |
Aliases |
KLRB1; NKR; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A |
Entrez GeneID |
3820 |
Swissprot |
Q12918 |
clone |
4C6A11 |
WB Predicted band size |
25.4kDa |
Host/Isotype |
Mouse IgG2b |
Antibody Type |
Primary antibody |
Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity |
Human |
Immunogen |
Purified recombinant fragment of human CD161 (AA: extra 67-225) expressed in E. Coli. |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Application |
FCM
|
1/200 - 1/400 |
ELISA |
1/10000
|
Product Image |