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CD162
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ELISA
FCM
IHC
- Catalog： TD-32295
- Clonality： mAb
- Application： IHC, FCM
- Synonyms： CLA; SELPLG; PSGL1; PSGL-1
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD162
| Description | |
| This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants. | |
| Specification | |
| Aliases | CLA; SELPLG; PSGL1; PSGL-1 |
| Entrez GeneID | 6404 |
| Swissprot | Q14242 |
| clone | 3D5E11 |
| WB Predicted band size | 43.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD162 (AA: 42-320) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of THP-1 cells using CD162 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using CD162 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CD162 mouse mAb with DAB staining.
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