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CD170
All
ELISA
FCM
  • CatalogTD-31588
  • ClonalitymAb
  • Application FCM
  • SynonymsSIGLEC5; OBBP2; CD33L2; OB-BP2; SIGLEC-5
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD170


Description
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
 
Specification
Aliases SIGLEC5; OBBP2; CD33L2; OB-BP2; SIGLEC-5
Entrez GeneID 8778
Swissprot O15389
clone 3F5A3
WB Predicted band size 60.7kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-315881.jpg
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
TD-315882.jpg
Flow cytometric analysis of HL-60 cells using CD170 mouse mAb (green) and negative control (red).