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CD172b
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ELISA
IF
FCM
- Catalog： TD-32214
- Clonality： mAb
- Application： IHC, IF, FCM
- Synonyms： SIRPB1; SIRP-BETA-1
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD172b
| Description | |
| The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. |
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| Specification | |
| Aliases | SIRPB1; SIRP-BETA-1 |
| Entrez GeneID | 10326 |
| Swissprot | O00241 |
| clone | 1B1G4 |
| WB Predicted band size | 43.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD172b (AA: extra 72-309) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| IHC | 1/200 - 1/1000 |
| IF | 1/50 - 1/200 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using CD172b mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of K562 cells using CD172b mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using CD172b mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human prostate cancer tissues using CD172b mouse mAb with DAB staining.
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