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CD177
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ELISA
WB
FCM
- Catalog： TD-31584
- Clonality： mAb
- Application： WB, FCM
- Synonyms： NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD177
| Description | |
| This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. |
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| Specification | |
| Aliases | NB1; PRV1; HNA2A; PRV-1; HNA-2a; NB1 GP |
| Entrez GeneID | 57126 |
| Swissprot | Q8N6Q3 |
| clone | 2F2C1 |
| WB Predicted band size | 46.4kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD177 (AA: extra 22-161) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD177 mouse mAb against SPC-A-1 (1), SK-MES-1 (2), HepG2 (3), HL-60 (4), and PC-3 (5) cell lysate.
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Flow cytometric analysis of HL-60 cells using CD177 mouse mAb (green) and negative control (red).
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