The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.
Specification
Aliases
VPREB1; IGI; IGVPB; VPREB
Entrez GeneID
7441
Swissprot
P12018
clone
5F8F3
WB Predicted band size
16.6kDa
Host/Isotype
Mouse IgG1
Antibody Type
Primary antibody
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD179A (AA: extra 20-145) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Application
FCM
1/200 - 1/400
ELISA
1/10000
Product Image
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of MOLT4 cells using CD179A mouse mAb (green) and negative control (red).