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CD191
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ELISA
WB
FCM
- Catalog： TD-31395
- Clonality： mAb
- Application： WB, FCM
- Synonyms： CCR1; CKR1; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD191
| Description | |
| This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. | |
| Specification | |
| Aliases | CCR1; CKR1; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1 |
| Entrez GeneID | 1230 |
| Swissprot | P32246 |
| clone | 8E10F9 |
| WB Predicted band size | 41.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD191 (AA: extra mix) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| WB | 1/500 - 1/2000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using CD191 mouse mAb against HepG2 (1) cell lysate.
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Flow cytometric analysis of Ramos cells using CD191 mouse mAb (green) and negative control (red).
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