抗体
试剂盒
多肽
探针
蛋白
组织芯片
产品中心
Product Center
CD207
All
ELISA
FCM
定制服务咨询
Mouse Monoclonal Antibody to CD207
| Description | |
| The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. | |
| Specification | |
| Aliases | CLEC4K |
| Entrez GeneID | 50489 |
| Swissprot | Q9UJ71 |
| clone | 1C5A1 |
| WB Predicted band size | 36.7kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD207 (AA: extra 155-328) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
|
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
|
Flow cytometric analysis of K562 cells using CD207 mouse mAb (green) and negative control (red).
|