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CD抗体
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CD210
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ELISA
IF
FCM
  • CatalogTD-32169
  • ClonalitymAb
  • Application FCM, IF
  • SynonymsIL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
  • 规格
    100ul 50ul
  • 价格
    ¥2180
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Mouse Monoclonal Antibody to CD210


Description
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
 
Specification
Aliases IL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Entrez GeneID 3587
Swissprot Q13651
clone 8A2A5
WB Predicted band size 63kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD210 (AA: extra 22-235)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Application
IF 1/25 - 1/200
FCM 1/200 - 1/400
ELISA 1/10000
Product Image
TD-321691.jpg
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
TD-321693.jpg
Immunofluorescence analysis of Hela cells using CD210 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
TD-321692.jpg
Flow cytometric analysis of THP-1 cells using CD210 mouse mAb (green) and negative control (red).