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CD360
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- Catalog： TD-32158
- Clonality： mAb
- Application： IF, FCM
- Synonyms： IL21R; NILR; IMD56
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规格：
100ul 50ul
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价格：
¥2180
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Mouse Monoclonal Antibody to CD360
| Description | |
| The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. |
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| Specification | |
| Aliases | IL21R; NILR; IMD56 |
| Entrez GeneID | 50615 |
| Swissprot | Q9HBE5 |
| clone | 1C3G9 |
| WB Predicted band size | 59.1kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD360 (AA: extra 20-232) expressed in HEK293-6e cells supernatant |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
| Application | |
| IF | 1/25 - 1/200 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
| Product Image | |
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using CD360 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of K562 cells using CD360 mouse mAb (green) and negative control (red).
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